Liposomes as Drug Carriers: Classification, Preparation Methods, and Medicinal Use

Liposomes are one of the most well-known and promising nanoscale drug delivery systems. Liposomal medicinal products successfully used in clinical practice for cardiovascular, oncological, dermatological, other indications. The development liposomes their widespread implementation relevant tasks. aim study was to summarise analyse scientific data regarding structure, composition, classification liposomes, as well specific aspects liposome production methods. This review covers up-to-date information on marketed liposomal products. authors illustrate how methods affect composition structure liposomes. size lamellarity important characteristics that determine encapsulation efficiency biodistribution active pharmaceutical ingredients (APIs). choice excipients depends intended use article summarises main methods, highlighting usage aspects, advantages disadvantages. Conventional easy apply do not require complex equipment, principal disadvantages include low API within high complexity scaling up technological processes. pay special attention microfluidic techniques preparation, which characterised by a highly controlled process (in terms distribution lamellarity), reproducibility, scalability level industrial applicable encapsulating different APIs.